Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan trametiglue CA-Lissamine Rhodamine B is a

CA-Lissamine Rhodamine B is a HaloTag Ligand containg Lissamine Rhodamine B dye and it forms a covalent bond with the HaloTag protein

506 SMILES OC(=O)CCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

79 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)OCC#C)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

DBCO-Biotin is a biotinylation reagent

Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan trametiglue CA-Lissamine Rhodamine B is aSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent